/* Peptide Registry — dark-pastel theme (per brand guidelines) */

:root {
  --bg-primary: #070A0F;
  --bg-secondary: #0D1118;
  --bg-card: #121824;
  --bg-card-2: #0F1420;

  --text-primary: #F5F7FA;
  --text-secondary: #C9D1DC;
  --text-muted: #8F9AAA;
  --text-disabled: #5E6877;

  --border-subtle: #263142;

  --accent-gold: #FFE7A3;
  --accent-coral: #FF9D7A;
  --accent-rose: #F6A6D8;
  --accent-violet: #BBA7FF;
  --accent-blue: #7CCBFF;
  --accent-cyan: #A7F3FF;
  --accent-mint: #9FF3D0;

  --gradient-primary: linear-gradient(90deg,#FFE7A3 0%,#FF9D7A 22%,#F6A6D8 44%,#BBA7FF 63%,#7CCBFF 82%,#A7F3FF 100%);
  --gradient-cool: linear-gradient(90deg,#BBA7FF 0%,#7CCBFF 50%,#A7F3FF 100%);
  --gradient-hero: linear-gradient(90deg,#FFE7A3 0%,#FF9D7A 35%,#BBA7FF 65%,#7CCBFF 100%);

  --radius-sm: 10px;
  --radius-md: 16px;
  --radius-lg: 24px;
  --radius-pill: 999px;

  --shadow-soft: 0 24px 80px rgba(0,0,0,0.35);

  --max-width-page: 1200px;
  --max-width-copy: 760px;

  --font-sans: "Inter", system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  --font-mono: "IBM Plex Mono", ui-monospace, SFMono-Regular, Menlo, monospace;
}

* { box-sizing: border-box; }

html {
  background: var(--bg-primary);
  color: var(--text-primary);
  font-family: var(--font-sans);
  text-rendering: optimizeLegibility;
  -webkit-font-smoothing: antialiased;
  scroll-behavior: smooth;
}
body {
  margin: 0;
  background:
    radial-gradient(circle at 50% -10%, rgba(124,203,255,0.10), rgba(7,10,15,0) 45%),
    radial-gradient(circle at 90% 5%, rgba(255,157,122,0.06), rgba(7,10,15,0) 40%),
    var(--bg-primary);
  color: var(--text-secondary);
  min-height: 100vh;
  font-size: 16px;
  line-height: 1.6;
}
h1,h2,h3,h4 { color: var(--text-primary); letter-spacing: -0.03em; margin: 0; line-height: 1.1; }
p { margin: 0; }
a { color: inherit; text-decoration: none; }
a:hover { color: var(--text-primary); }

.container { width: min(100% - 48px, var(--max-width-page)); margin-inline: auto; }
.gradient-text {
  background: var(--gradient-hero);
  -webkit-background-clip: text; background-clip: text;
  -webkit-text-fill-color: transparent; color: transparent;
}
.mono { font-family: var(--font-mono); }

/* ---------- Nav ---------- */
.nav {
  position: sticky; top: 0; z-index: 50;
  background: rgba(7,10,15,0.78);
  backdrop-filter: blur(18px);
  border-bottom: 1px solid rgba(255,255,255,0.06);
}
.nav-inner {
  width: min(100% - 48px, var(--max-width-page));
  margin-inline: auto; min-height: 68px;
  display: flex; align-items: center; justify-content: space-between; gap: 24px;
}
.nav-logo { display: flex; align-items: center; gap: 10px; font-weight: 800; letter-spacing: -0.04em; font-size: 19px; color: var(--text-primary); }
.nav-logo .mark {
  width: 26px; height: 26px; border-radius: 8px; display: block;
  box-shadow: 0 6px 22px rgba(124,203,255,0.30);
}
.nav-right { display: flex; align-items: center; gap: 18px; }
.nav-links { display: flex; gap: 20px; }
.nav-links a { color: var(--text-secondary); font-size: 14px; font-weight: 500; }
.nav-links a:hover { color: var(--text-primary); }

/* ---------- Hero / search ---------- */
.hero { padding: 64px 0 28px; text-align: center; }
.hero .eyebrow {
  font-family: var(--font-mono); font-size: 12px; letter-spacing: 0.18em; text-transform: uppercase;
  color: var(--accent-blue); margin-bottom: 18px;
}
.hero h1 { font-size: clamp(38px, 6.4vw, 72px); font-weight: 800; letter-spacing: -0.05em; line-height: 0.98; }
.hero p.sub { color: var(--text-secondary); font-size: clamp(16px,2vw,20px); max-width: 640px; margin: 18px auto 0; }

.searchbar { max-width: 720px; margin: 34px auto 0; position: relative; }
.searchbar input {
  width: 100%; background: var(--bg-secondary); color: var(--text-primary);
  border: 1px solid var(--border-subtle); border-radius: var(--radius-pill);
  padding: 17px 22px 17px 52px; font: inherit; font-size: 17px;
}
.searchbar input::placeholder { color: var(--text-muted); }
.searchbar input:focus { outline: none; border-color: var(--accent-blue); box-shadow: 0 0 0 4px rgba(124,203,255,0.12); }
.searchbar .icon { position: absolute; left: 20px; top: 50%; transform: translateY(-50%); color: var(--text-muted); font-size: 18px; }
.searchbar .clear { position: absolute; right: 16px; top: 50%; transform: translateY(-50%); color: var(--text-muted); cursor: pointer; font-size: 18px; padding: 6px; display: none; }
.searchbar .clear:hover { color: var(--text-primary); }

/* ---------- Layout ---------- */
.layout { display: grid; grid-template-columns: 268px 1fr; gap: 36px; padding: 30px 0 100px; align-items: start; }
@media (max-width: 900px) { .layout { grid-template-columns: 1fr; } .filters { position: static !important; } }

/* ---------- Filters ---------- */
.filters { position: sticky; top: 92px; }
.filter-group { margin-bottom: 26px; }
.filter-group h4 {
  font-family: var(--font-mono); font-size: 11px; letter-spacing: 0.14em; text-transform: uppercase;
  color: var(--text-muted); margin-bottom: 12px;
}
.chips { display: flex; flex-wrap: wrap; gap: 8px; }
.chip {
  display: inline-flex; align-items: center; gap: 6px; cursor: pointer;
  background: rgba(255,255,255,0.03); color: var(--text-secondary);
  border: 1px solid var(--border-subtle); border-radius: var(--radius-pill);
  padding: 6px 12px; font-size: 13px; font-weight: 500; transition: all 140ms ease;
  user-select: none;
}
.chip:hover { border-color: var(--accent-blue); color: var(--text-primary); }
.chip.active { background: rgba(124,203,255,0.12); border-color: rgba(124,203,255,0.5); color: var(--text-primary); }
.chip .count { font-family: var(--font-mono); font-size: 11px; color: var(--text-muted); }
.chip.active .count { color: var(--accent-cyan); }

.reset-btn {
  font-size: 13px; color: var(--text-muted); cursor: pointer; background: none; border: none;
  font-family: var(--font-mono); padding: 0; margin-top: 4px;
}
.reset-btn:hover { color: var(--accent-blue); }

/* ---------- Results ---------- */
.results-head { display: flex; align-items: center; justify-content: space-between; margin-bottom: 18px; flex-wrap: wrap; gap: 12px; }
.results-count { color: var(--text-muted); font-family: var(--font-mono); font-size: 13px; }
.results-count b { color: var(--text-primary); }
.sort-select { background: var(--bg-secondary); color: var(--text-secondary); border: 1px solid var(--border-subtle); border-radius: var(--radius-sm); padding: 8px 12px; font: inherit; font-size: 13px; }
.active-filters { display: flex; flex-wrap: wrap; gap: 8px; margin-bottom: 18px; }
.active-filters .chip.removable { background: rgba(187,167,255,0.12); border-color: rgba(187,167,255,0.4); color: var(--text-primary); }

.grid { display: grid; grid-template-columns: repeat(auto-fill, minmax(280px, 1fr)); gap: 22px; }

.card {
  background: rgba(18,24,36,0.82);
  border: 1px solid rgba(124,203,255,0.12);
  border-radius: var(--radius-lg);
  box-shadow: var(--shadow-soft);
  padding: 24px; cursor: pointer; display: flex; flex-direction: column; gap: 12px;
  transition: transform 160ms ease, border-color 160ms ease;
}
.card:hover { transform: translateY(-3px); border-color: rgba(124,203,255,0.4); }
.card .card-top { display: flex; flex-wrap: wrap; align-items: flex-start; justify-content: space-between; gap: 8px 10px; }
.card .card-top > div { min-width: 0; flex: 1 1 auto; }
.card .card-top .tier { flex-shrink: 0; }
.card h3 { font-size: 20px; font-weight: 700; }
.card .class-label { font-family: var(--font-mono); font-size: 11px; color: var(--text-muted); letter-spacing: 0.04em; margin-top: 3px; }
.card p.snippet { color: var(--text-secondary); font-size: 14.5px; line-height: 1.55; display: -webkit-box; -webkit-line-clamp: 3; -webkit-box-orient: vertical; overflow: hidden; }
.card .card-tags { display: flex; flex-wrap: wrap; gap: 6px; margin-top: auto; }

/* tag pills */
.pill {
  display: inline-flex; align-items: center; gap: 6px;
  background: rgba(124,203,255,0.08); color: var(--accent-cyan);
  border: 1px solid rgba(167,243,255,0.18); border-radius: var(--radius-pill);
  padding: 4px 10px; font-size: 12px; font-weight: 600; font-family: var(--font-mono);
}
.pill.plain { background: rgba(255,255,255,0.03); color: var(--text-muted); border-color: var(--border-subtle); cursor: pointer; }
.pill.plain:hover { color: var(--text-primary); border-color: var(--accent-blue); }

/* evidence tier badges */
.tier {
  display: inline-flex; align-items: center; gap: 6px; white-space: nowrap;
  border-radius: var(--radius-pill); padding: 5px 11px; font-size: 12px; font-weight: 700;
  font-family: var(--font-mono); letter-spacing: 0.02em; border: 1px solid;
}
.tier::before { content:""; width:7px; height:7px; border-radius:50%; background: currentColor; }
.tier-fda-approved   { color:#9FF3D0; background:rgba(159,243,208,0.10); border-color:rgba(159,243,208,0.30); }
.tier-human-rct      { color:#7CCBFF; background:rgba(124,203,255,0.10); border-color:rgba(124,203,255,0.30); }
.tier-trials-ongoing { color:#A7F3FF; background:rgba(167,243,255,0.10); border-color:rgba(167,243,255,0.28); }
.tier-human-small    { color:#FFE7A3; background:rgba(255,231,163,0.10); border-color:rgba(255,231,163,0.30); }
.tier-animal         { color:#FF9D7A; background:rgba(255,157,122,0.10); border-color:rgba(255,157,122,0.30); }
.tier-in-vitro       { color:#FF9D7A; background:rgba(255,157,122,0.08); border-color:rgba(255,157,122,0.25); }
.tier-no-human-trials{ color:#F6A6D8; background:rgba(246,166,216,0.10); border-color:rgba(246,166,216,0.32); }

/* status chips */
.status-chip { display:inline-flex; align-items:center; gap:6px; font-size:12px; font-weight:600; font-family:var(--font-mono); color:var(--text-muted); border:1px solid var(--border-subtle); background:rgba(255,255,255,0.02); border-radius:var(--radius-pill); padding:4px 10px; }

/* ---------- Detail view ---------- */
.detail { max-width: 880px; margin: 0 auto; padding: 24px 0 110px; }
.back-link { display:inline-flex; align-items:center; gap:8px; font-family:var(--font-mono); font-size:13px; color:var(--text-muted); margin-bottom: 26px; cursor:pointer; }
.back-link:hover { color: var(--accent-blue); }
.detail-head { margin-bottom: 8px; }
.detail-head h1 { font-size: clamp(34px,5vw,52px); font-weight:800; letter-spacing:-0.05em; }
.detail-head .aka { color: var(--text-muted); font-size: 15px; margin-top: 8px; font-family: var(--font-mono); }
.detail-meta { display:flex; flex-wrap:wrap; gap:10px; align-items:center; margin: 18px 0 8px; }

.detail-section { margin-top: 40px; }
.detail-section > h2 {
  font-size: 14px; font-family: var(--font-mono); letter-spacing: 0.12em; text-transform: uppercase;
  color: var(--accent-blue); margin-bottom: 16px; padding-bottom: 10px; border-bottom: 1px solid var(--border-subtle);
}
.lead { font-size: 19px; line-height: 1.6; color: var(--text-secondary); max-width: var(--max-width-copy); }

.callout {
  border-radius: var(--radius-md); padding: 18px 22px; margin-top: 8px;
  background: rgba(255,231,163,0.06); border: 1px solid rgba(255,231,163,0.22);
  color: var(--text-secondary); line-height: 1.55;
}
.callout .label { font-family: var(--font-mono); font-size:11px; letter-spacing:0.12em; text-transform:uppercase; color: var(--accent-gold); display:block; margin-bottom:6px; }

.itemlist { display: flex; flex-direction: column; gap: 12px; }
.item {
  display: flex; gap: 14px; align-items: flex-start;
  background: var(--bg-card-2); border: 1px solid var(--border-subtle); border-radius: var(--radius-md); padding: 16px 18px;
}
.item .body { flex: 1; }
.item .body .txt { color: var(--text-secondary); line-height: 1.55; }
.item .body .sub { color: var(--text-muted); font-size: 13px; margin-top: 5px; font-family: var(--font-mono); }

/* citation marker */
.cite-ref {
  font-family: var(--font-mono); font-size: 11px; font-weight: 700; vertical-align: super;
  color: var(--accent-blue); cursor: pointer; padding: 0 2px; border-bottom: 1px dotted rgba(124,203,255,0.5);
}
.cite-ref:hover { color: var(--accent-cyan); }

/* trials table */
.table-wrap { overflow-x: auto; border: 1px solid var(--border-subtle); border-radius: var(--radius-md); }
table.trials { width: 100%; border-collapse: collapse; font-size: 13.5px; min-width: 640px; }
table.trials th { text-align: left; font-family: var(--font-mono); font-size: 11px; letter-spacing: 0.08em; text-transform: uppercase; color: var(--text-muted); padding: 12px 14px; border-bottom: 1px solid var(--border-subtle); background: rgba(255,255,255,0.02); }
table.trials td { padding: 12px 14px; border-bottom: 1px solid rgba(38,49,66,0.5); color: var(--text-secondary); vertical-align: top; }
table.trials tr:last-child td { border-bottom: none; }
table.trials a { color: var(--accent-blue); font-family: var(--font-mono); }
table.trials a:hover { color: var(--accent-cyan); }

/* doctor takes */
.take { background: var(--bg-card-2); border: 1px solid var(--border-subtle); border-left: 3px solid var(--accent-violet); border-radius: 0 var(--radius-md) var(--radius-md) 0; padding: 16px 20px; }
.take .who { font-weight: 700; color: var(--text-primary); font-size: 15px; }
.take .verdict { color: var(--accent-violet); font-family: var(--font-mono); font-size: 12.5px; margin: 3px 0 8px; }
.take .quote { color: var(--text-secondary); line-height: 1.55; font-size: 14.5px; }
.take .vid { display:inline-block; margin-top:8px; font-family:var(--font-mono); font-size:12px; color: var(--accent-blue); }
.take.unverified { border-left-color: var(--accent-rose); }
.take.unverified .verdict { color: var(--accent-rose); }

/* sources list */
.sources-list { counter-reset: src; display: flex; flex-direction: column; gap: 10px; }
.source-item { display: flex; gap: 12px; padding: 12px 16px; background: var(--bg-card-2); border: 1px solid var(--border-subtle); border-radius: var(--radius-sm); }
.source-item .num { font-family: var(--font-mono); font-size: 12px; color: var(--accent-blue); font-weight: 700; min-width: 24px; }
.source-item .src-body a { color: var(--accent-blue); word-break: break-word; }
.source-item .src-body a:hover { color: var(--accent-cyan); }
.source-item .src-type { font-family: var(--font-mono); font-size: 10px; text-transform: uppercase; letter-spacing: 0.1em; padding: 2px 7px; border-radius: var(--radius-pill); border: 1px solid var(--border-subtle); color: var(--text-muted); margin-left: 8px; }
.source-item.flash { animation: flash 1.4s ease; }
@keyframes flash { 0%,100%{ background: var(--bg-card-2);} 20%{ background: rgba(124,203,255,0.14);} }

.risk-list { display:flex; flex-wrap:wrap; gap:8px; }
.risk { background: rgba(246,166,216,0.07); border:1px solid rgba(246,166,216,0.2); color: var(--text-secondary); border-radius: var(--radius-pill); padding: 6px 13px; font-size: 13.5px; }

/* disclaimer / legend */
.legend { display:flex; flex-wrap:wrap; gap:10px; margin-top: 16px; padding: 16px 18px; background: var(--bg-secondary); border:1px solid var(--border-subtle); border-radius: var(--radius-md); }
.legend .li { display:flex; align-items:center; gap:7px; font-size:12px; color: var(--text-muted); font-family: var(--font-mono); }
.legend .li .dot { width:8px;height:8px;border-radius:50%; }

.disclaimer { margin-top: 50px; padding: 18px 22px; border: 1px dashed var(--border-subtle); border-radius: var(--radius-md); color: var(--text-muted); font-size: 13.5px; line-height: 1.55; }

.empty { text-align:center; padding: 80px 0; color: var(--text-muted); }
.empty h3 { color: var(--text-secondary); margin-bottom: 8px; }

/* footer */
.footer { background:#05070B; border-top:1px solid rgba(255,255,255,0.06); padding: 48px 0; color: var(--text-muted); font-size: 13.5px; }
.footer .container { display:flex; justify-content:space-between; flex-wrap:wrap; gap:16px; }
.footer a { color: var(--text-secondary); }

::-webkit-scrollbar { height: 10px; width: 10px; }
::-webkit-scrollbar-thumb { background: var(--border-subtle); border-radius: 10px; }
::-webkit-scrollbar-track { background: transparent; }

/* =========================================================
   v2 — larger type, gradient card titles, filters, glossary,
   component relationships
   ========================================================= */

/* (1) card titles → brand gradient + larger card body text */
.card h3 {
  font-size: 23px;
  background: var(--gradient-hero);
  -webkit-background-clip: text; background-clip: text;
  -webkit-text-fill-color: transparent; color: transparent;
}
.card .class-label { font-size: 13px; margin-top: 5px; }
.card p.snippet { font-size: 16.5px; line-height: 1.6; -webkit-line-clamp: 4; }
.card .card-tags .pill { font-size: 13px; padding: 5px 11px; }

/* detail page name also gradient (one strong phrase per page) */
.detail-head h1 {
  background: var(--gradient-hero);
  -webkit-background-clip: text; background-clip: text;
  -webkit-text-fill-color: transparent; color: transparent;
  padding-bottom: 4px;
}
.detail-head .aka { font-size: 16px; }

/* (3) filters — much larger titles + chips */
.filter-group h4 {
  font-size: 16px;
  letter-spacing: 0.04em;
  color: var(--text-secondary);
  margin-bottom: 14px;
  display: flex; align-items: center; justify-content: space-between;
}
.filter-group h4.toggle { cursor: pointer; user-select: none; }
.filter-group h4.toggle:hover { color: var(--text-primary); }
.filter-group h4 .caret { font-size: 13px; color: var(--text-muted); transition: transform 160ms ease; }
.filter-group.collapsed h4 .caret { transform: rotate(-90deg); }
.filter-group.collapsed .chips { display: none; }
.chip { font-size: 15px; padding: 8px 15px; }
.chip .count { font-size: 12px; }

/* (4) larger titles & callouts site-wide */
.detail-section > h2 { font-size: 18px; letter-spacing: 0.08em; margin-bottom: 18px; }
.lead { font-size: 21px; line-height: 1.6; }
.callout { font-size: 18px; line-height: 1.6; padding: 22px 26px; }
.callout .label { font-size: 13px; margin-bottom: 8px; }
.hero .eyebrow { font-size: 13px; }
.item .body .txt { font-size: 17px; line-height: 1.55; }
.item .body .sub { font-size: 14px; }
.take .who { font-size: 18px; }
.take .verdict { font-size: 14px; }
.take .quote { font-size: 16.5px; }
.results-count { font-size: 15px; }
.source-item .src-body { font-size: 15.5px; }
.risk { font-size: 15px; }
.status-chip { font-size: 13px; }
.tier { font-size: 13px; }

/* (2) component relationships */
.found-in {
  margin: 18px 0 6px; padding: 16px 20px; border-radius: var(--radius-md);
  background: rgba(159,243,208,0.06); border: 1px solid rgba(159,243,208,0.22);
}
.found-in .label { font-family: var(--font-mono); font-size: 13px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--accent-mint); display:block; margin-bottom: 10px; }
.blend-links { display: flex; flex-wrap: wrap; gap: 10px; }
.blend-link {
  display: inline-flex; align-items: center; gap: 8px; cursor: pointer;
  background: rgba(255,255,255,0.03); border: 1px solid var(--border-subtle);
  border-radius: var(--radius-pill); padding: 8px 16px; font-size: 15px; font-weight: 600; color: var(--text-primary);
}
.blend-link:hover { border-color: var(--accent-mint); background: rgba(159,243,208,0.08); }
.blend-link .arrow { color: var(--accent-mint); }

.components-grid { display: grid; grid-template-columns: repeat(auto-fill, minmax(240px,1fr)); gap: 14px; }
.component-card {
  display: flex; flex-direction: column; gap: 6px; cursor: pointer;
  background: var(--bg-card-2); border: 1px solid var(--border-subtle); border-radius: var(--radius-md); padding: 16px 18px;
  transition: border-color 140ms ease, transform 140ms ease;
}
.component-card:hover { border-color: var(--accent-blue); transform: translateY(-2px); }
.component-card .cc-name { font-weight: 700; color: var(--accent-blue); font-size: 17px; }
.component-card .cc-role { color: var(--text-muted); font-size: 14px; }
.component-card .cc-go { font-family: var(--font-mono); font-size: 12px; color: var(--text-muted); margin-top: 2px; }

/* (5) glossary — inline terms, page glossary, popover, master page */
.gterm { border-bottom: 1px dotted rgba(124,203,255,0.55); color: var(--text-primary); cursor: pointer; }
.gterm:hover { color: var(--accent-cyan); border-bottom-color: var(--accent-cyan); }

.page-glossary { margin-top: 8px; }
.gloss-chips { display: flex; flex-wrap: wrap; gap: 8px; }
.gloss-chip {
  cursor: pointer; font-family: var(--font-mono); font-size: 14px;
  background: rgba(187,167,255,0.08); color: var(--accent-violet);
  border: 1px solid rgba(187,167,255,0.25); border-radius: var(--radius-pill); padding: 6px 13px;
}
.gloss-chip:hover { background: rgba(187,167,255,0.16); color: var(--text-primary); }
.page-glossary .hint { color: var(--text-muted); font-size: 14px; margin-bottom: 12px; }

.gloss-popover {
  position: absolute; z-index: 100; max-width: 420px; width: max-content;
  background: var(--bg-card); border: 1px solid rgba(187,167,255,0.4); border-radius: var(--radius-md);
  box-shadow: var(--shadow-soft); padding: 18px 20px; display: none;
}
.gloss-popover.show { display: block; }
.gloss-popover h5 { font-size: 18px; color: var(--text-primary); margin: 0 0 4px; letter-spacing: -0.02em; }
.gloss-popover .cat { font-family: var(--font-mono); font-size: 11px; text-transform: uppercase; letter-spacing: 0.1em; color: var(--accent-violet); margin-bottom: 10px; }
.gloss-popover .row { margin-top: 10px; }
.gloss-popover .row .k { font-family: var(--font-mono); font-size: 11px; text-transform: uppercase; letter-spacing: 0.08em; color: var(--text-muted); display: block; margin-bottom: 2px; }
.gloss-popover .row .v { color: var(--text-secondary); font-size: 15px; line-height: 1.5; }
.gloss-popover .def { color: var(--text-primary); font-size: 16px; line-height: 1.55; }
.gloss-popover .close { position: absolute; top: 12px; right: 14px; cursor: pointer; color: var(--text-muted); font-size: 18px; }
.gloss-popover .close:hover { color: var(--text-primary); }

/* master glossary page */
.glossary-page { max-width: 980px; margin: 0 auto; padding: 30px 0 110px; }
.glossary-page h1 { font-size: clamp(34px,5vw,52px); font-weight: 800; letter-spacing: -0.04em; margin-bottom: 10px; }
.gloss-cards { display: grid; grid-template-columns: repeat(auto-fill, minmax(340px,1fr)); gap: 18px; margin-top: 24px; }
.gcard { background: var(--bg-card); border: 1px solid var(--border-subtle); border-radius: var(--radius-lg); padding: 22px 24px; }
.gcard h3 { font-size: 21px; margin-bottom: 3px; }
.gcard .cat { font-family: var(--font-mono); font-size: 11px; text-transform: uppercase; letter-spacing: 0.1em; color: var(--accent-violet); margin-bottom: 12px; }
.gcard .def { color: var(--text-primary); font-size: 16px; line-height: 1.55; }
.gcard .row { margin-top: 12px; }
.gcard .row .k { font-family: var(--font-mono); font-size: 11px; text-transform: uppercase; letter-spacing: 0.08em; color: var(--text-muted); display:block; margin-bottom: 3px; }
.gcard .row .v { color: var(--text-secondary); font-size: 15px; line-height: 1.5; }
.gcard .row.deriv .v { font-style: italic; color: var(--text-muted); }

/* (6) layman-first + collapsible blocks */
.plain-block { margin-top: 18px; }
.plain-block .plabel { font-family: var(--font-mono); font-size: 13px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--accent-mint); margin-bottom: 10px; display:block; }
.plain-lead { font-size: 22px; line-height: 1.6; color: var(--text-primary); max-width: var(--max-width-copy); }

.cblock { margin-top: 18px; border: 1px solid var(--border-subtle); border-radius: var(--radius-md); overflow: hidden; }
.cblock-head {
  display: flex; align-items: center; justify-content: space-between; cursor: pointer; user-select: none;
  padding: 15px 20px; background: rgba(255,255,255,0.02);
  font-family: var(--font-mono); font-size: 14px; letter-spacing: 0.08em; text-transform: uppercase; color: var(--text-secondary);
}
.cblock-head:hover { color: var(--text-primary); }
.cblock-head .cb-caret { transition: transform 160ms ease; color: var(--text-muted); }
.cblock-body { padding: 0 20px; max-height: 0; overflow: hidden; transition: max-height 240ms ease, padding 240ms ease; }
.cblock.open .cblock-body { max-height: 2400px; padding: 18px 20px; }
.cblock.open .cb-caret { transform: rotate(180deg); }
.cblock-body p { color: var(--text-secondary); font-size: 17px; line-height: 1.6; }
.cblock-body p + p { margin-top: 12px; }
.cblock-body .tlabel { font-family: var(--font-mono); font-size: 11px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--text-muted); display:block; margin: 4px 0 6px; }

/* AI ask */
.ask-row { max-width: 720px; margin: 14px auto 0; display: flex; align-items: center; justify-content: center; gap: 12px; flex-wrap: wrap; }
.ask-hint { color: var(--text-muted); font-size: 14px; }
.ask-btn {
  display: inline-flex; align-items: center; gap: 8px; cursor: pointer;
  background: var(--gradient-cool); color: var(--bg-primary); border: none;
  border-radius: var(--radius-pill); padding: 11px 20px; font: inherit; font-weight: 700; font-size: 15px;
  transition: transform 160ms ease, filter 160ms ease;
}
.ask-btn:hover { filter: brightness(1.08); transform: translateY(-1px); }
.ask-btn:disabled { opacity: 0.6; cursor: default; transform: none; }
.ask-answer { max-width: 820px; margin: 26px auto 0; text-align: left; }
.ask-card {
  background: rgba(18,24,36,0.9); border: 1px solid rgba(187,167,255,0.3);
  border-radius: var(--radius-lg); box-shadow: var(--shadow-soft); padding: 26px 30px;
}
.ask-card .ask-q { font-family: var(--font-mono); font-size: 13px; color: var(--accent-violet); letter-spacing: 0.04em; margin-bottom: 14px; }
.ask-card .ask-body { color: var(--text-secondary); font-size: 17px; line-height: 1.62; white-space: pre-wrap; }
.ask-card .ask-body strong { color: var(--text-primary); }
.ask-card .ask-used { margin-top: 20px; padding-top: 16px; border-top: 1px solid var(--border-subtle); display: flex; flex-wrap: wrap; gap: 8px; align-items: center; }
.ask-card .ask-used .lbl { font-family: var(--font-mono); font-size: 11px; text-transform: uppercase; letter-spacing: 0.1em; color: var(--text-muted); margin-right: 4px; }
.ask-loading { display: inline-flex; align-items: center; gap: 10px; color: var(--text-secondary); font-size: 16px; }
.ask-loading .dot { width: 9px; height: 9px; border-radius: 50%; background: var(--accent-violet); animation: pulse 1s ease-in-out infinite; }
@keyframes pulse { 0%,100%{ opacity: 0.3; transform: scale(0.8);} 50%{ opacity:1; transform: scale(1);} }
.ask-disclaimer { color: var(--text-muted); font-size: 13px; margin-top: 14px; }

/* names & nomenclature */
.name-note { margin: 16px 0 4px; padding: 16px 20px; border-radius: var(--radius-md); background: rgba(124,203,255,0.05); border: 1px solid rgba(124,203,255,0.18); }
.name-note .label { font-family: var(--font-mono); font-size: 12px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--accent-blue); display: block; margin-bottom: 8px; }
.name-note .nn-body { color: var(--text-secondary); font-size: 16px; line-height: 1.55; }
.name-note .nn-src { margin-top: 10px; font-family: var(--font-mono); font-size: 12.5px; color: var(--text-muted); }
.name-note .nn-src a { color: var(--accent-blue); }
.name-note .nn-src a:hover { color: var(--accent-cyan); }

/* ============================================================
   Detail page v3 — pepipedia-style layout, dark-pastel theme,
   larger fonts. Tabs + regulatory banner + safety sidebar.
   ============================================================ */

/* regulatory status banner */
.reg-banner { display:flex; gap:16px; align-items:flex-start; margin:14px 0 26px; padding:18px 22px;
  border-radius: var(--radius-md); border:1px solid rgba(255,157,122,0.30);
  background: linear-gradient(90deg, rgba(255,157,122,0.10), rgba(246,166,216,0.06)); }
.reg-banner .reg-ico { flex:0 0 auto; width:30px; height:30px; border-radius:50%; display:flex; align-items:center; justify-content:center;
  font-family:var(--font-mono); font-weight:700; font-size:18px; color:var(--bg-primary); background:var(--accent-coral); }
.reg-banner .reg-title { font-size:18.5px; font-weight:700; color:var(--accent-gold); line-height:1.4; }
.reg-banner .reg-sub { font-size:15.5px; color:var(--text-secondary); margin-top:5px; line-height:1.5; }

/* two-column grid */
.detail-grid { display:grid; grid-template-columns: minmax(0,1fr) 320px; gap:28px; align-items:start; }
.detail-main { min-width:0; }
.detail-side { position:sticky; top:24px; display:flex; flex-direction:column; gap:18px; }
@media (max-width: 900px){ .detail-grid { grid-template-columns:1fr; } .detail-side { position:static; } }

/* header */
.detail-head h1 { font-size:42px; line-height:1.08; }
.detail-head .aka { font-family:var(--font-mono); font-size:15px; color:var(--text-muted); margin-top:10px; line-height:1.6; }
.detail-head .detail-meta { display:flex; flex-wrap:wrap; gap:10px; margin-top:16px; }

/* tabs */
.detail-tabs { margin-top:26px; }
.tab-nav { display:flex; flex-wrap:wrap; gap:6px; border-bottom:1px solid var(--border-subtle); margin-bottom:26px; }
.tab-btn { appearance:none; background:none; border:none; cursor:pointer; font-family:var(--font-sans);
  font-size:18px; font-weight:600; color:var(--text-muted); padding:12px 16px; position:relative; transition:color .15s; }
.tab-btn:hover { color:var(--text-secondary); }
.tab-btn.active { color:var(--text-primary); }
.tab-btn.active::after { content:""; position:absolute; left:12px; right:12px; bottom:-1px; height:3px; border-radius:3px 3px 0 0; background:var(--gradient-hero); }
.tab-pane { display:none; animation:fadein .2s ease; }
.tab-pane.active { display:block; }
@keyframes fadein { from{opacity:0; transform:translateY(4px);} to{opacity:1; transform:none;} }

/* headings inside panes — larger */
.detail-main h2 { font-size:27px; font-weight:700; margin:30px 0 14px; color:var(--text-primary); }
.detail-main h2:first-child { margin-top:0; }
.detail-main h2.what-is { font-size:30px; }
.detail-main .h2-sub { text-transform:none; font-family:var(--font-sans); color:var(--text-muted); font-size:14px; letter-spacing:0; font-weight:500; }
.moa { font-size:18px; line-height:1.7; color:var(--text-secondary); }
.plain-block .plain-lead { font-size:19px; line-height:1.65; }

/* info cards (Primary research focus / Class / Regulatory / Evidence) */
.info-cards { display:grid; grid-template-columns:repeat(2,1fr); gap:14px; margin:22px 0 6px; }
@media (max-width:560px){ .info-cards { grid-template-columns:1fr; } }
.info-card { padding:18px 20px; border-radius:var(--radius-md); background:var(--bg-card-2); border:1px solid var(--border-subtle); }
.info-card .ic-label { font-family:var(--font-mono); font-size:12.5px; letter-spacing:.06em; text-transform:uppercase; color:var(--text-muted); }
.info-card .ic-val { font-size:18px; font-weight:600; color:var(--text-primary); margin-top:7px; line-height:1.4; }

.empty-tab { font-size:17px; color:var(--text-muted); padding:18px 0; }

/* sidebar cards */
.side-card { padding:22px; border-radius:var(--radius-md); background:var(--bg-card); border:1px solid var(--border-subtle); }
.side-card h3 { font-size:20px; font-weight:700; margin-bottom:16px; }
.ss-row { padding:14px 0; border-top:1px solid var(--border-subtle); }
.ss-row:first-of-type { border-top:none; padding-top:0; }
.ss-row .ss-k { font-family:var(--font-mono); font-size:12.5px; letter-spacing:.05em; text-transform:uppercase; color:var(--accent-blue); margin-bottom:6px; }
.ss-row .ss-v { font-size:16px; line-height:1.55; color:var(--text-secondary); }

/* legal box */
.legal-box { margin-top:30px; border-radius:var(--radius-md); border:1px solid rgba(124,203,255,0.22);
  border-left:4px solid var(--accent-blue); background:rgba(124,203,255,0.05); padding:20px 24px; }
.legal-box .lb-head { font-size:18px; font-weight:700; color:var(--accent-blue); margin-bottom:10px; }
.legal-box .lb-body { font-size:15.5px; line-height:1.65; color:var(--text-secondary); }
.sources-block { margin-top:30px; }

/* widen the detail view for the two-column layout */
.detail { max-width: 1120px; }
@media (max-width: 900px){ .detail { max-width: 880px; } }

/* ============================================================
   v4 refinements (requests 2–5)
   ============================================================ */

/* (3) larger eyebrow / label text site-wide */
.callout .label, .found-in .label, .plain-block .plabel, .name-note .label { font-size: 15px; letter-spacing: 0.09em; }
.cblock-head { font-size: 16px; }
.cblock-body .tlabel { font-size: 13.5px; }
.info-card .ic-label, .ss-row .ss-k { font-size: 14px; }
.source-item .src-type { font-size: 12px; padding: 3px 9px; }
.filter-group h4 { font-size: 13px; }
.page-glossary .hint { font-size: 15.5px; }

/* (5) other-names box now lists the names; naming explanation sits in "What is" */
.name-note .nn-names { font-family: var(--font-mono); font-size: 16px; line-height: 1.95; color: var(--text-secondary); }
.plain-block .naming-para { margin-top: 16px; }  /* inherit the lead: same size + white as the first paragraph */

/* (4) Hype vs reality — Proven / Hyped split with a centered partial line */
.callout p { margin: 0; }
.callout .hype-div { width: 70px; height: 2px; border-radius: 2px; margin: 18px auto; background: var(--gradient-hero); opacity: 0.6; }

/* (2) source-type chips colored to brand palette */
.src-type.src-paper, .src-type.src-meta-analysis { color: var(--accent-mint); border-color: rgba(159,243,208,0.55); }
.src-type.src-registry, .src-type.src-trial { color: var(--accent-blue); border-color: rgba(124,203,255,0.55); }
.src-type.src-regulatory { color: var(--accent-cyan); border-color: rgba(167,243,255,0.55); }
.src-type.src-reference { color: var(--accent-violet); border-color: rgba(187,167,255,0.6); }
.src-type.src-doctor, .src-type.src-doctor-commentary { color: var(--accent-gold); border-color: rgba(255,231,163,0.55); }
.src-type.src-vendor { color: var(--accent-coral); border-color: rgba(255,157,122,0.55); }
.src-type.src-wikipedia, .src-type.src-ref { color: var(--accent-violet); border-color: rgba(187,167,255,0.6); }

/* ============================================================
   Reconstitution calculator + Learn page
   ============================================================ */
.recon-calc { margin: 22px 0; padding: 22px 24px; border-radius: var(--radius-md);
  background: linear-gradient(180deg, rgba(124,203,255,0.06), rgba(187,167,255,0.04));
  border: 1px solid rgba(124,203,255,0.22); }
.recon-calc .rc-head { font-family: var(--font-mono); font-size: 14px; letter-spacing: 0.06em; text-transform: uppercase; color: var(--accent-blue); margin-bottom: 16px; }
.recon-calc .rc-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; }
@media (max-width: 620px) { .recon-calc .rc-grid { grid-template-columns: 1fr; } }
.rc-field { display: flex; flex-direction: column; gap: 7px; }
.rc-field .rc-lab { font-size: 14px; color: var(--text-secondary); }
.rc-field .rc-inp { display: flex; align-items: center; gap: 8px; background: var(--bg-secondary); border: 1px solid var(--border-subtle); border-radius: var(--radius-sm); padding: 0 12px; }
.rc-field .rc-inp:focus-within { border-color: var(--accent-blue); box-shadow: 0 0 0 3px rgba(124,203,255,0.12); }
.rc-field input { flex: 1; min-width: 0; background: none; border: none; color: var(--text-primary); font: inherit; font-size: 18px; padding: 11px 0; outline: none; }
.rc-field .rc-inp em { font-family: var(--font-mono); font-size: 14px; color: var(--text-muted); font-style: normal; }
.recon-calc .rc-out { margin-top: 16px; padding: 16px 18px; border-radius: var(--radius-sm); background: rgba(0,0,0,0.25); border: 1px solid var(--border-subtle); font-size: 18px; line-height: 1.6; color: var(--text-secondary); }
.recon-calc .rc-out b { color: var(--accent-cyan); font-weight: 700; }
.recon-calc .rc-note { margin-top: 12px; font-size: 13.5px; color: var(--text-muted); line-height: 1.5; }

/* Learn page */
.learn-body { max-width: 780px; margin: 0 auto; }
.learn-body .plain-lead { font-size: 20px; }
.tier-legend { display: flex; flex-direction: column; gap: 12px; margin: 18px 0 6px; }
.tier-legend .tl-row { display: flex; align-items: center; gap: 14px; }
.tier-legend .tl-desc { font-size: 16.5px; color: var(--text-secondary); }

/* ============================================================
   Learn/Terms column align · unit defs · needle · calc select · footer
   ============================================================ */
.learn .learn-col { max-width: 820px; margin: 0 auto; }
.learn h2 { font-size: 27px; font-weight: 700; margin: 32px 0 14px; color: var(--text-primary); }
.learn .plain-lead { font-size: 20px; }
.learn .moa { font-size: 18px; line-height: 1.7; color: var(--text-secondary); }
.learn .moa b { color: var(--text-primary); }

/* unit definitions (mg / mcg / mL / units / mg-per-mL) */
.unit-defs { display: flex; flex-direction: column; gap: 10px; margin: 8px 0 20px; }
.unit-defs .ud { display: grid; grid-template-columns: 96px 1fr; gap: 14px; align-items: baseline; padding: 13px 16px; border-radius: var(--radius-sm); background: var(--bg-card-2); border: 1px solid var(--border-subtle); }
.unit-defs .ud-k { font-family: var(--font-mono); font-size: 16px; font-weight: 700; color: var(--accent-cyan); }
.unit-defs .ud-v { font-size: 16.5px; line-height: 1.55; color: var(--text-secondary); }
.unit-defs .ud-v b { color: var(--text-primary); }
@media (max-width: 520px){ .unit-defs .ud { grid-template-columns: 1fr; gap: 4px; } }

/* labeled insulin-syringe diagram */
.needle-wrap { margin: 6px 0 20px; padding: 18px 20px 14px; border-radius: var(--radius-md); background: var(--bg-card-2); border: 1px solid var(--border-subtle); }
.needle-svg { width: 100%; height: auto; display: block; }
.needle-cap { margin-top: 6px; font-size: 15px; color: var(--text-muted); line-height: 1.55; text-align: center; }
.needle-cap b { color: var(--accent-cyan); }

/* calculator: syringe <select>, warnings, responsive grid */
.recon-calc .rc-grid { grid-template-columns: repeat(auto-fit, minmax(165px, 1fr)); }
.rc-sel { padding-right: 8px; }
.rc-sel select { flex: 1; min-width: 0; background: none; border: none; color: var(--text-primary); font: inherit; font-size: 15px; padding: 12px 0; outline: none; cursor: pointer; }
.rc-sel select option { background: var(--bg-secondary); color: var(--text-primary); }
.recon-calc .rc-warn { color: var(--accent-coral); font-weight: 600; }
.recon-calc .rc-ok { color: var(--text-muted); font-size: 15px; }

/* strong global footer disclaimer (every page) */
.footer { border-top: 1px solid var(--border-subtle); margin-top: 50px; padding: 30px 0 64px; background: rgba(0,0,0,0.28); }
.footer .container { display: block; }
.footer-disclaimer { font-size: 15px; line-height: 1.65; color: var(--text-secondary); border: 1px solid rgba(255,157,122,0.32); background: rgba(255,157,122,0.06); border-radius: var(--radius-md); padding: 18px 22px; }
.footer-disclaimer strong { color: var(--text-primary); }
.footer-disclaimer a { color: var(--accent-blue); text-decoration: underline; }
.footer-meta { display: flex; flex-wrap: wrap; justify-content: space-between; gap: 8px; margin-top: 16px; font-size: 13px; color: var(--text-muted); font-family: var(--font-mono); }
.footer-meta a { color: var(--accent-blue); }